KMID : 1034420230480020012
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Restorative Dentistry & Endodontics 2023 Volume.48 No. 2 p.12 ~ p.12
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Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors
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Douglas Augusto Roderjan
Rodrigo Stanislawczuk Diana Gabriela Soares Carlos Alberto de Souza Costa Michael Willian Favoreto Alessandra Reis Alessandro D. Loguercio
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Abstract
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Objectives: The present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP).
Materials and Methods: The following groups were compared: 35% HP (HP35; n = 5) or 20% HP (HP20; n = 4). In the control group (CONT; n = 2), no dental bleaching was performed. The color change (CC) was registered at baseline and after 2 days using the Vita Classical shade guide. Tooth sensitivity (TS) was also recorded for 2 days post-bleaching. The teeth were extracted 2 days after the clinical procedure and subjected to histological analysis. The CC and overall scores for histological evaluation were evaluated by the Kruskal-Wallis and Mann-Whitney tests. The percentage of patients with TS was evaluated by the Fisher exact test (¥á = 0.05).
Results: The CC and TS of the HP35 group were significantly higher than those of the CONT group (p < 0.05) and the HP20 group showed an intermediate response, without significant differences from either the HP35 or CONT group (p > 0.05). In both experimental groups, the coronal pulp tissue exhibited partial necrosis associated with tertiary dentin deposition. Overall, the subjacent pulp tissue exhibited a mild inflammatory response.
Conclusions: In-office bleaching therapies using bleaching gels with 20% or 35% HP caused similar pulp damage to the mandibular incisors, characterized by partial necrosis, tertiary dentin deposition, and mild inflammation.
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KEYWORD
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Hydrogen peroxide, In-office bleaching, Odontoblasts
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